$169.00 / month
Monthly prescription program
Bi-Est Cream is a bioidentical estrogen therapy that combines estriol and estradiol in a balanced 50/50 ratio, offering gentle yet effective hormonal support. Designed to mimic the body’s natural estrogen profile, Bi-Est helps address common symptoms associated with hormonal decline while promoting overall balance and comfort.
As estrogen levels shift due to age, menopause, or hormonal changes, individuals may experience hot flashes, mood changes, sleep disruption, and decreased skin elasticity. Bi-Est Cream delivers consistent estrogen support through topical application, allowing for smooth absorption and steady hormonal levels.
Our compounded Bi-Est Cream is prescribed based on your individual needs and delivered as part of a convenient monthly program. With pharmaceutical-grade formulation and clinical oversight, this therapy supports symptom relief, balance, and long-term wellness.
Benefits may include:
Whether you’re seeking a softer estrogen approach or a balanced solution for long-term hormonal support, daily Bi-Est Cream offers a flexible, science-backed path to feeling steady and supported.
Balance hormones. Support comfort. Feel aligned again.
This topical estrogen blend is intended for women who are post-menopausal and experiencing symptoms associated with decreased estrogen. Licensed providers determine appropriate dosing and frequency based on individual health history and symptom profile.
HRT products are not available in the following states: CA, CO, IA, WA, and WI.
Out of stock

Bi-Est Cream is a compounded bioidentical estrogen therapy that combines two forms of estrogen estriol and estradiol in a balanced 50/50 ratio. Designed to support women with low estrogen levels, it helps restore hormonal balance during menopause or other estrogen-deficient states. By delivering estrogen through the skin, Bi-Est Cream supports relief from symptoms such as hot flashes, night sweats, vaginal dryness, and mood changes, while promoting overall hormonal stability and well-being.

Bi-Est Cream delivers a balanced combination of estriol and estradiol two key forms of estrogen naturally produced by the body. This 50/50 blend works by supporting estrogen receptors involved in hormone regulation, helping maintain balance across systems that affect mood, energy, skin health, bone density, and overall well-being. Applied topically, the cream allows for steady absorption, offering a more consistent and controlled way to support hormonal harmony, especially during times of hormonal decline or transition.

From the first few applications, many users notice a gentle sense of balance often describing improved mood stability, calmer energy, and reduced hot flashes or night discomfort. Over the following weeks, users commonly report feeling more like themselves again, with better sleep quality, steadier energy levels, and improved skin comfort. The cream is generally well tolerated, with any initial sensitivity typically easing as the body adjusts to consistent estrogen support.


At Vyora, we believe wellness should be straightforward, science-backed, and sustainable. Whether you’re looking to support metabolic health, boost energy, or enhance vitality, our personalized solutions are designed to help you thrive.
Vyora goes beyond weight management to offer a holistic range of treatments tailored to you. With science-backed medications, expert guidance, and community support, we’re redefining what it means to live well. We’re pioneers, who believe in a gentler, smarter approach to GLP-1 therapy—microdosing that supports lasting weight loss, emotional balance, and metabolic health without the harsh side effects

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Washington
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